A rising star
Key Industries
With South Dakota ranked #2 on the Tax Foundation’s State Tax Competitiveness Index, our community is a leading destination for your business. Low business costs, a dependable, growing workforce and well-established infrastructure are just a few of the reasons why more businesses are choosing Sioux Falls.
Major Employers
Diverse industries call for diverse organizations. Sioux Falls has 13 companies with 1,000 or more employees.
As of August 7, 2025
| Company | Industry | Employees |
|---|---|---|
| Sanford Health / Evangelical Lutheran Good Samaritan Society | Biomedical | 10,500-11,000 |
| Avera Health | Biomedical | 8,000-8,500 |
| Sioux Falls School District | Education | 3,500-4,000 |
| Smithfield Foods | Food Processing | 3,000-3,500 |
| Hy-Vee Food Stores | Retail | 2,000-2,500 |
| Wells Fargo | Finance & Banking | 1,500-2,000 |
| Walmart/Sam’s Club | Retail & Wholesale | 1,500-2,000 |
| City of Sioux Falls | Government | 1,500-2,000 |
| Amazon | E-commerce | 1,500-2,000 |
| Citi | Finance & Banking | 1,000-1,500 |
| Department of Veterans Affairs Medical & Regional Office | Healthcare / Government | 1,000-1,500 |
| First PREMIER Bank/PREMIER Bankcard | Finance & Banking | 1,000-1,500 |
| LifeScape | Healthcare & Social Services | 1,000-1,500 |
| MIDCO | Data Centers | 750-800 |
| Showplace Cabinetry | Manufacturing | 750-800 |
| Billion Automotive Companies | Retail | 650-700 |
| StarMark Cabinetry | Manufacturing | 650-700 |
| Lewis Drug | Biomedical | 600-650 |
| Minnehaha County | Government | 550-600 |
| Sammons Financial Group | Finance & Banking | 550-600 |
| Augustana University | Education | 500-550 |
| CNH/Raven Industries | Manufacturing | 500-550 |
| Daktronics | Manufacturing | 500-550 |
| GreatLife Malaska Golf & Fitness | Services | 500-550 |
| Scheels | Retail | 500-550 |