Household names
Major Employers
Sioux Falls is growing. We have a diversified economy providing a stable mix of industries. Join our corporate community and grow alongside regional and national powerhouses that call Sioux Falls home.
Updated 5/6/25
| Company | Industry | Employees |
|---|---|---|
| Sanford Health / Evangelical Good Samaritan Society | Biomedical | 10,500-11,000 |
| Avera Health | Biomedical | 8,000-8,500 |
| Sioux Falls School District | Education | 3,500-4,000 |
| Smithfield Foods | Food Processing | 3,000-3,500 |
| Hy-Vee Food Stores | Retail | 2,000-2,500 |
| Amazon | E-commerce | 1,500-2,000 |
| City of Sioux Falls | Government | 1,500-2,000 |
| Walmart/Sam’s Club | Retail & Wholesale | 1,500-2,000 |
| Wells Fargo | Finance & Banking | 1,500-2,000 |
| Citi | Finance & Banking | 1,000-1,500 |
| Department of Veterans Affairs Medical & Regional Office | Healthcare / Government | 1,000-1,500 |
| First PREMIER Bank/PREMIER Bankcard | Finance & Banking | 1,000-1,500 |
| LifeScape | Healthcare & Social Services | 1,000-1,500 |
| MIDCO | Data Centers | 750-800 |
| Showplace Cabinetry | Manufacturing | 700-750 |
| Billion Automotive Companies | Retail | 650-700 |
| StarMark Cabinetry | Manufacturing | 650-700 |
| Lewis Drug | Biomedical | 600-650 |
| Minnehaha County | Government | 600-650 |
| Sammons Financial Group | Finance & Banking | 550-600 |
| Augustana University | Education | 500-550 |
| CNH Industrial / Raven Industries | Manufacturing | 500-550 |
| Daktronics | Manufacturing | 500-550 |
| GreatLife Malaska Golf & Fitness | Services | 500-550 |
| Scheels | Retail | 500-550 |