Doing business in Sioux Falls

South Dakota is one of the most business-friendly states in the country. And there’s no better place to settle down and take advantage of those incentives than in Sioux Falls. As the state’s largest city with a metro population of 318,000 (2025), Sioux Falls has low business costs with a high quality of life. There’s no state, corporate or personal income tax, no inheritance tax and no limits to what your business can achieve.